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Portal:Biology

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Introduction

A panoramic view from a ridge located between Segla and Hesten mountain summits in the island of Senja, Troms, Norway in 2014
A panoramic view from a ridge located between Segla and Hesten mountain summits in the island of Senja, Troms, Norway in 2014

Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, origin, evolution, and distribution of life. Central to biology are five fundamental themes: the cell as the basic unit of life, genes and heredity as the basis of inheritance, evolution as the driver of biological diversity, energy transformation for sustaining life processes, and the maintenance of internal stability (homeostasis).

Biology examines life across multiple levels of organization, from molecules and cells to organisms, populations, and ecosystems. Subdisciplines include molecular biology, physiology, ecology, evolutionary biology, developmental biology, and systematics, among others. Each of these fields applies a range of methods to investigate biological phenomena, including observation, experimentation, and mathematical modeling. Modern biology is grounded in the theory of evolution by natural selection, first articulated by Charles Darwin, and in the molecular understanding of genes encoded in DNA. The discovery of the structure of DNA and advances in molecular genetics have transformed many areas of biology, leading to applications in medicine, agriculture, biotechnology, and environmental science.

Life on Earth is believed to have originated over 3.7 billion years ago. Today, it includes a vast diversity of organisms—from single-celled archaea and bacteria to complex multicellular plants, fungi, and animals. Biologists classify organisms based on shared characteristics and evolutionary relationships, using taxonomic and phylogenetic frameworks. These organisms interact with each other and with their environments in ecosystems, where they play roles in energy flow and nutrient cycling. As a constantly evolving field, biology incorporates new discoveries and technologies that enhance the understanding of life and its processes, while contributing to solutions for challenges such as disease, climate change, and biodiversity loss. (Full article...)

Adenosine triphosphate (ATP) is a nucleoside triphosphate that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis. Found in all known forms of life, it is often referred to as the "molecular unit of currency" for intracellular energy transfer.

When consumed in a metabolic process, ATP converts either to adenosine diphosphate (ADP) or to adenosine monophosphate (AMP). Other processes regenerate ATP. It is also a precursor to DNA and RNA, and is used as a coenzyme. An average adult human processes around 50 kilograms (about 100 moles) daily. (Full article...)

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Photo credit: Bernard Landgraf
The Red Panda (Ailurus fulgens) is a small bear-like mammal native to the Himalayas and southern China.

Major topics

History History of biology | timeline of biology and organic chemistry | history of ecology | history of evolutionary thought | history of geology | history of model organisms | history of molecular biology | history of paleontology
Overview Biology | science | life | properties (adaptationenergy processinggrowthorderregulationreproduction, and response to environment) | hierarchy of life (atommoleculeorganellecelltissueorganorgan systemorganismpopulationcommunityecosystembiosphere) | reductionistic | emergent property | mechanistic | scientific method | theory | law | peer review | biology journals
Chemical basis Matter | elements | compounds | atoms | molecules | chemical bonds | carbon | organic compounds | macromolecules | carbohydrate | protein | protein structure | protein folding | lipid | DNA | RNA
Cells Prokaryote | eukaryote | cell wall | cell membrane | cytoskeleton | mitochondrion | chloroplast | nucleus | endoplasmic reticulum | Golgi apparatus | cell cycle | mitosis | metabolism | cell signaling | protein targeting | metabolism | enzyme | glycolysis | citric acid cycle | electron transport chain | oxidative phosphorylation |photosynthesis |meiosis  | mitosis
Genetics (Intro) Classical genetics | mendelian inheritance | gene | phenotype | genotype | ploidy | alternation of generations | molecular genetics | gene expression | gene regulation | genome | karyotype | DNA replication | transcription | translation | recombination | chromosome | epigenetics | splicing | mutation | genetic fingerprint | chromatin | ecological genetics | population genetics | quantitative genetics
Evolution (Intro)  | omne vivum ex ovo | Natural selection | genetic drift | sexual selection | speciation | mutation | gene flow | evolution of sex | biogeography | cladistics | species | extinction | tree of life | phylogenies | three-domain system
Diversity Bacteria | archaea | plants | angiosperms | fungi | protists | Animals | deuterostome | insects | molluscs | nematodes | parasitism | Primate | mammal | vertebrate | craniata | chordate | viruses
Plant form and function Epidermis | flower | ground tissue  | leaf | phloem | plant stem | root | shoot | vascular plant | vascular tissue | xylem
Animal form and function Tissues | fertilization | embryogenesis | gastrulation | neurulation | organogenesis | differentiation | morphogenesis | metamorphosis | ontogeny  | Development | senescence  | reproduction | oogenesis | spermatogenesis
Ecology Ecosystem | biomass | food chain | indicator species | habitat | species distribution | Gaia theory | metapopulation  | life cycle | Life history | altricial - precocial | sex ratio | altruism | cooperation - foraging | learning | parental care | sexual conflict | territoriality | biosphere | climate change | conservation | biodiversity | nature reserve | edge effect | allee effect | corridor | fragmentation | pollution | invasive species | in situ - ex situ | seedbank
Research methods Laboratory techniques | Genetic engineering | transformation | gel electrophoresis | chromatography | centrifugation | cell culture | DNA sequencing | DNA microarray | green fluorescent protein | vector | enzyme assay | protein purification | Western blot | Northern blot | Southern blot | restriction enzyme | polymerase chain reaction | two-hybrid screening | in vivo - in vitro - in silico | Field techniques | Belt transect | mark and recapture | species discovery curve
Branches Anatomy | biotechnology | botany | cell biology | ecology | evolutionary biology | genetics | marine biology | microbiology | molecular biology | mycology | neuroscience | paleontology | phycology | physiology | protistology | virology | zoology
Awards Nobel Prize in Physiology or Medicine
See also Template:History of biology

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McClintock in her laboratory, 1947

Barbara McClintock (June 16, 1902 – September 2, 1992) was an American scientist and cytogeneticist who was awarded the 1983 Nobel Prize in Physiology or Medicine. McClintock received her PhD in botany from Cornell University in 1927. There she started her career as the leader of the development of maize cytogenetics, the focus of her research for the rest of her life. From the late 1920s, McClintock studied chromosomes and how they change during reproduction in maize. She developed the technique for visualizing maize chromosomes and used microscopic analysis to demonstrate many fundamental genetic ideas. One of those ideas was the notion of genetic recombination by crossing-over during meiosis—a mechanism by which chromosomes exchange information. She is often credited with producing the first genetic map for maize, linking regions of the chromosome to physical traits. However this legend has been corrected by Kass (2024). She demonstrated the role of the telomere and centromere, regions of the chromosome that are important in the conservation of genetic information. She was recognized as among the best in the field, awarded prestigious fellowships, and elected a member of the National Academy of Sciences in 1944.

During the 1940s and 1950s, McClintock discovered transposons and used it to demonstrate that genes are responsible for turning physical characteristics on and off. She developed theories to explain the suppression and expression of genetic information from one generation of maize plants to the next. Due to skepticism of her research and its implications, she stopped publishing her data in 1953. (Full article...)

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